منابع مشابه
Cellular switches orchestrate rhythmic circuits
Small inhibitory neuronal circuits have long been identified as key neuronal motifs to generate and modulate the coexisting rhythms of various motor functions. Our paper highlights the role of a cellular switching mechanism to orchestrate such circuits. The cellular switch makes the circuits reconfigurable, robust, adaptable, and externally controllable. Without this cellular mechanism, the cir...
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Development of stem and progenitor cells into specialized tissues in multicellular organisms involves a series of cell fate decisions. Cellular differentiation in higher organisms is generally considered irreversible, and the idea of developmental plasticity in postnatal tissues is controversial. Here, we show that inhibition of mitogen-activated protein kinase (MAPK) in a human bone marrow str...
متن کاملHigh-dimensional switches and the modeling of cellular differentiation
Olivier Cinquin 1,2,3,∗ & Jacques Demongeot 3 1: CoMPLEX, UCL 2:Department of Anatomy and Developmental Biology University College London Gower Street, London WC1E 6BT, U.K. 3:Laboratoire TIMC-IMAG-CNRS UMR 5525, Université Joseph Fourier, Grenoble 1 Faculté de Médecine, Domaine de la Merci, 38706 La Tronche, France * Correspondence: [email protected] Journal of Theoretical Biology 233(3), pp...
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This report examines a specific nanoscale computing technology, namely Magnetic Quantum Cellular Automata (MQCA) systems. It provides estimates of the temperature stability and operating speed as a function of the device size, together with estimates of how such systems might behave if the device sizes could be scaled down to molecular dimensions. REPORT DOCUMENTATION PAGE Form Approved OMB No....
متن کاملHigh-dimensional switches and the modelling of cellular differentiation.
Many genes have been identified as driving cellular differentiation, but because of their complex interactions, the understanding of their collective behaviour requires mathematical modelling. Intriguingly, it has been observed in numerous developmental contexts, and particularly haematopoiesis, that genes regulating differentiation are initially co-expressed in progenitors despite their antago...
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ژورنال
عنوان ژورنال: IEEE Transactions on Magnetics
سال: 2004
ISSN: 0018-9464
DOI: 10.1109/tmag.2004.828991